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A01
A01-1 Noji-Team
- Ryunosuke Hayashi, Kazuo Kasaki, Shuichi Nakamura, Seishi Kudo, Yuichi Inoue, Hiroyuki Noji and Kumiko Hayashi
"Giant acceleration of diffusion observed in a single-molecule experiment on F 1-ATPase"
Physical Review Letters, 114:248101, 2015 - Jun-ichi Kishikawa, Akihiko Seino, Atsuko Nakanishi, Naciye Esma Tirtom, Hiroyuki Noji, Ken Yokoyama and Kumiko Hayashi
"F-subunit reinforces torque generation in V-ATPase"
European Biophysics Journal, 43:415-422, 2014 - Taro Ichimura, Liang-da Chiu, Katsumasa Fujita, Satoshi Kawata, Tomonobu M. Watanabe, Toshio Yanagida, Hideaki Fujita
"Visualizing Cell State Transition Using Raman Spectroscopy"
PLoS One, 9:e84478, 2014 - Sayaka Higuchi, Tomonobu M. Watanabe, Keiko Kawauchi, Taro Ichimura and Hideaki Fujita
"Culturing of mouse and human cells on soft substrates promote the expression of stem cell markers."
Journal of Bioscience and Bioengineering, S1389-1723(13):434-439, 2013 - Taka-aki Yano, Taro Ichimura, Shota Kuwahara, Fekhra H’Dhili, Kazumasa Uetsuki, Yoshito Okuno, Prabhat Verma, and Satoshi Kawata
"Tip-enhanced nano-Raman analytical imaging of locally induced strain distribution in carbon nanotubes"
Nature Communications, 4:2592, 2013 - Tomonobu M. Watanabe, Katsumi Imada, Keiko Yoshizawa, Masayoshi Nishijima, Chiaki Kato, Fumiyoshi Abe, Takamitsu J. Morikawa, Miki Kinoshita, Hideaki Fujita and Toshio Yanagida
"Glycine Insertion Makes Yellow Fluorescent Protein Sensitive to Hydrostatic Pressure."
PLoS PNE, 8(8):e73212, 2013 - Tomonobu M. Watanabe, Fumihiko Fujii, Takashi Jin, Eiji Umemoto, Masayuki Miyasaka, Hideaki Fujita and Toshio Yanagida
"Four-Dimensional Spatial Nanometry of Single Particles in Living Cells Using Polarized Quantum Rods."
Biophysical Journal, 105(3):555-564, 2013 - Masami Yamada, Kanako Kumamoto, Shintaro Mikuni, Yoshiyuki Arai, Masataka Kinjo, Takeharu Nagai, Yoshikazu Tsukasaki, Tomonobu M Watanabe, Mitsuru Fukui, Mingyue Jin, Shiori Toba and Shinji Hirotsune
"Rab6a releases LIS1 from a dynein idling complex and activates dynein for retrograde movement."
Nature Communications, 4:2033, 2013 - Jun Yu, Yuika Saito, Taro Ichimura, Satoshi Kawata and Prabhat Verma
"Far-field free tapping-mode tip-enhanced Raman microscopy."
Applied Physics Letters, 102(12):123110, 2013 - Togo Shimozawa, Kazuo Yamagata, Takefumi Kondo, Shigeo Hayashi, Atsunori Shitamukai, Daijiro Konno, Fumio Matsuzaki, Jun Takayama, Shuichi Onami, Hiroshi Nakayama, Yasuhito Kosugi, Tomonobu M. Watanabe, Katsumasa Fujita, Yuko Mimori-Kiyosue
"Improving spinning disk confocal microscopy by preventing pinhole cross-talk for intravital imaging."
PNAS, 110(9):3399-3404, 2013 - Naciye Esma Tirtom, Daichi Okuno, Masahiro Nakano, Ken Yokoyama and Hiroyuki Noji
"Mechanical Modulation of ATP-binding Affinity of V1-ATPase."
The Journal of Biological Chemistry, 288:619-623, 2013 - Sawako Enoki, Ryota Iino, Nobuhiro Morone, Kunihiro Kaihatsu, Shouichi Sakakihara, Nobuo Kato and Hiroyuki Noji
"Label-free single-particle imaging of the influenza virus by objective-type total internal reflection dark-field microscopy"
PLoS ONE, 7:e49208, 1-7, 2012 - Takahiro Muraoka, Tatsuya Shima, Tsutomu Hamada, Masamune Morita, Masahiro Takagi, Kazuhito V. Tabata, Hiroyuki Noji, and Kazushi Kinbara
"Ion Permeation by a Folded Multiblock Amphiphilic Oligomer Achieved by Hierarchical Construction of Self-Assembled Nanopores"
Journal of The American Chemical Society, 134:19788-19794, 2012 - Huijuan You, Ryota Iino, Rikiya Watanabe and Hiroyuki Noji
"Winding single-molecule double-stranded DNA on a nanometer-sized reel."
Nucleic Acids Research, 40(19):e151, 2012 - Mizue Tanigawara, Kazuhito V. Tabata, Yuko Ito, Jotaro Ito, Rikiya Watanabe, Hiroshi Ueno, Mitsunori Ikeguchi and Hiroyuki Noji
"Role of the DELSEED Loop in Torque Transmission of F1-ATPase"
Biophysical Journal, 103:970-978, 2012 - Tomonobu M. Watanabe, Yoshikazu Tsukasaki, Hideaki Fujita, Taro Ichimura, Tatsuya Saitoh, Shizuo Akira, and Toshio Yanagida
"Distinct modulated pupil function system for real-time imaging of living cells."
PlosOne, 7:e44028, 2012 - Noriyuki Hatsugai, Vadim Perez Koldenkova, Hiromi Imamura, Hiroyuki Noji and Takeharu Nagai
"Changes in Cytosolic ATP Levels and Intracellular Morphology during Bacteria-Induced Hypersensitive Cell Death as Revealed by Real-Time Fluorescence Microscopy Imaging"
Plant and Cell Physiology, 53:1768-1775, 2012 - Qiang Ma, Yuko Nakane, Yuki Mori, Miyuki Hasegawa, Yoshichika Yoshioka, Tomonobu M.Watanabe, Kohsuke Gonda, Noriaki Ohuchi and Takashi Jin.
"Multilayered, core/shell nanoprobes based on magnetic ferric oxide particles and quantum dots for multimodality imaging of breast cancer tumors."
Biomaterials, 33:8486-94, 2012 - Naciye Esma Uner, Yoshihiro Nishikawa, Daichi Okuno, Masahiro Nakano, Ken Yokoyama and Hiroyuki Noji
"Single-molecule analysis of inhibitory pausing states of V1-ATPase"
The Journal of Biological Chemistry, 287:28327-28335, 2012 - Soo Hyeon Kim , Shino Iwai , Suguru Araki , Shouichi Sakakihara , Ryota Iino and Hiroyuki Noji
"Large-scale femtoliter droplet array for digital counting of single biomolecules"
Lab on a Chip, 12:4986-4991, 2012 - Hayashi Yamamoto, Soichiro Kakuta, Tomonobu M. Watanabe, Akira Kitamura, Takayuki Sekito, Chika Kondo-Kakuta, Rie Ichikawa, Masataka Kinjo, and Yoshinori Ohsumi
"Atg9 vesicles are an important membrane source during early steps of autophagosome formation."
Journal of Cell Biology, 198:219-233, 2012 - Taro Ichimura, Hideaki Fujita, Keiko Yoshizawa and Tomonobu M. Watanabe
"Engineering strain-sensitive yellow fluorescent protein"
Chemical Communications, 48:7871-7873, 2012 - Ryota Iino, Kohei Hayama, Hiromi Amezawa, Shouichi Sakakihara, Soo Hyeon Kim, Yoshimi Matsumono, Kunihiko Nishino, Akihito Yamaguchi and Hiroyuki Noji
"A single-cell drug efflux assay in bacteria by using a directly accessible femtoliter droplet array"
Lab on a Chip, 12:3923-3929, 2012 - Takaaki Yano, Taro Ichimura, Shota Kuwahara, Prabhat Verma and Satoshi Kawata
"Subnanometric stabilization of plasmon-enhanced optical microscopy"
Nanotechnology, 23:205503, 2012 - Yoshihito Komoriya, Takayuki Ariga, Ryota Iino, Hiromi Imamura, Daichi Okuno and Hiroyuki Noji
"Principal Role of the Arginine Finger in Rotary Catalysis of F1-ATPase"
JOURNAL OF BIOLOGICAL CHEMISTRY, 287:15134-15142, 2012 - Shigehiko Hayashi, Hiroshi Ueno, Shaikh, Abdul Rajjak, Myco Umemura, Motoshi Kamiya, Yuko Ito, Mitsunori Ikeguchi, Yoshihito Komoriya, Ryota Iino and Hiroyuki Noji
"Molecular Mechanism of ATP Hydrolysis in F-1-ATPase Revealed by Molecular Simulations and Single-Molecule Observations"
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134:8447-8454, 2012 - Tomonobu Watanabe, Sayaka Higuchi, Keiko Kawauchi, Yoshikazu Tsukasaki, Taro Ichimura and Hideaki Fujita
"Chromatin plasticity as a differentiation index during muscle differentiation of C2C12 myoblasts."
Biochem Biophys Res Commun, 418:742, 2012 - Kiyotaka Sasagawa, Keisuke Ando, Takuma Kobayashi, Toshihiko Noda, Takashi Tokuda, Soo Hyeon Kim, Ryota Iino, Hiroyuki Noji, and Jun Ohta
"Complementary Metal-Oxide-Semiconductor Image Sensor with Microchamber Array for Fluorescent Bead Counting"
Japanese Journal of Applied Physics, 51:02BL01, 2012 - Rikiya Watanabe, Daichi Okuno, Shouichi Sakakihara, Katsuya Shimabukuro, Ryota Iino, Masasuke Yoshida & Hiroyuki Noji
"Mechanical modulation of catalytic power on F1-ATPase"
Nature Chemical Biology, 8:86–92, 2011
A01-2 Nagai-Team
- Tetsuichi Wazawa, Nobuyuki Morimoto, Takeharu Nagai and Makoto Suzuki
"Rotational motion of rhodamine 6G tethered to actin through oligo(ethylene glycol) linkers studied by frequency-domain fluorescence anisotropy"
Biophysics and Physicobiology, 12(2015):87-102, 2015 - Itsuo Hanasaki, Satoshi Uehara, Yoshiyuki Arai, Takeharu Nagai and Satoyuki Kawano
"Threshold-free evaluation of near-surface diffusion and adsorption-dominated motion from single-molecule tracking data of single-stranded DNA through TIRF"
Japanese Journal of Applied Physics, 54:12, 2015 - Koji L. Ode and Hiroki R. Ueda
"Seeing the forest and trees: whole-body and whole-brain imaging for circadian biology"
Diabetes, Obesity and Metabolism, 17 Suppl 1:47-54, 2015 - Karam Kim, Gurpreet Lakhanpal, Hsiangmin E. Lu, Mustafa Khan, Akio Suzuki, Mariko Kato Hayashi, Radhakrishnan Narayanan, Thomas T. Luyben, Tomoki Matsuda, Takeharu Nagai, Thomas A. Blanpied, Yasunori Hayashi and Kenichi Okamoto.
"A temporary gating mechanism of actin remodeling during sy 1 naptic plasticity consists of the interplay between the kinase and structural functions of CaMKII"
Neuron, 87(4):813-826, 2015 - Vadim Pérez Koldenkova, Tomoki Matsuda and Takeharu Nagai
"MagIC, a genetically encoded fluorescent indicator for monitoring cellular Mg2+ using a non-FRET ratiometric imaging approach"
Journal of Biomedical Optics, 20(10):101203, 2015 - Masahito Yamanaka, Kenta Saito, Nicholas I. Smith, Yoshiyuki Arai, Kumiko Uegaki, Yasuo Yonemaru, Kentaro Mochizuki, Satoshi Kawata, Takeharu Nagai and Katsumasa Fujita
"Visible-wavelength two-photon excitation microscopy for fluorescent protein imaging"
Journal of Biomedical Optics, 20(10):101202, 2015 - Shin-nosuke Uno, Dhermendra K. Tiwari, Mako Kamiya, Yoshiyuki Arai, Takeharu Nagai and Yasuteru Urano
"A guide to use photocontrollable fluorescent proteins and synthetic smart fluorophores for nanoscopy."
Microscopy, 0:1-15, 2015 - Kenta Saito and Takeharu Nagai
"Recent progress in luminescent proteins development"
Current Opinion In Chemical Biology, 27:46-51, 2015 - Akihiro Nezu, Takao Morita, Yosuke Tojyo,Takeharu Nagai and Akihiko Tanimura
"Partial agonistic effects of pilocarpine on Ca2+ responses and salivary secretion in the submandibular glands of live animals"
Experimental Physiology, 100:640-651, 2015 - Yoshiyuki Arai, Takayuki Yamamoto, Takeo Minamikawa, Tetsuro Takamatsu and Takeharu Nagai
"Spectral fingerprinting of individual cells visualized by cavity-reflection-enhanced light-absorption microscopy"
PLoS ONE, 10:125733, 2015 - Dhermendra K Tiwari, Yoshiyuki Arai, Masahito Yamanaka, Tomoki Matsuda, Masakazu Agetsuma, Masahiro Nakano, Katsumasa Fujita and Takeharu Nagai
"A fast- and positively photoswitchable fluorescent protein for ultralow-laser-power RESOLFT nanoscopy"
Nature Methods, 12:515-518, 2015 - Akira Takai, Masahiro Nakano, Kenta Saito, Remi Haruno, Tomonobu M. Watanabe, Tatsuya Ohyanagi, Takashi Jin, Yasushi Okada and Takeharu Nagai
"Expanded palette of Nano-lantern for real-time muliti-color luminescence imaging"
Proc. Natl. Acad. Sci. USA, 112:4352-4356, 2015 - Takeharu Nagai
"Real time imaging of biological phenomena with super-duper luminescent proteins"
CYTOLOGIA, 80:1-2, 2015 - Kazunori Sugiura,Takeharu Nagai,Masahiro Nakano,Hiroshi Ichinose,Takakazu Nakabayashi,Nobuhiro Ohta and Toru Hisabori
"Redox sensor proteins for highly sensitive direct imaging of intracellular redox state"
Biochemical and Biophysical Research Communications, 457(3):242-248, 2015 - Hiroyuki Ichijo, Michito Hamada, Satoru Takahashi, Makoto Kobayashi, Takeharu Nagai, Tomoko Toyama and Masahumi Kawaguchi
"Lateralization, maturation, and anteroposterior topography in the lateral habenula revealed by ZIF268/EGR1 immunoreactivity and labeling history of neuronal activity."
Neuroscience Reserach, 95:27-37, 2015 - Takahiro Muraoka, Nabanita Sadhukhan, Rui Li and Kazushi Kinbara
"Development of Self-Assembling Alternating Amphiphilic Compounds"
J. Photopolym. Sci. Tec., 27:557-560, 2014 - Shinji Yoshiyama, Zhenyi Chen, Tsuyoshi Okagaki, Kazuhiro Kohama, Ritsuko Nasu-Kawaharada, Takashi Izumi, Noriyasu Ohshima, Takeharu Nagai, and Akio Nakamura
"Nicotine exposure alters human vascular smooth muscle cell phenotype from a contractile to a synthetic type"
Atherosclerosis, 237:464-470, 2014 - Yoshiyuki Arai and Takeharu Nagai
"Real-Time Chemiluminescence Imaging Using Nano-Lantern Probes"
Current Protocols in Chemical Biology, 6:221-236, 2014 - Takeharu Nagai, Kazuki Horikawa,Kenta Saito and Tomiki Matsuda
"Genetically encoded Ca2+ indicators; expanded affinity range, color hue and compatibility with optogenetics"
Frontiers in Neuroscience, 7, 2014 - Yusuke Oshima, Takaeshi Imamura, Atsuko Shintani, Hiroko Kajiura-Kobayashi, Terumasa Hibi, Takeharu Nagai, shigenori Nonaka and Tomomi Nemoto
"Ultrasensitive imaging of Ca2+ dynamics in pancreatic acinar cells of Yellow Cameleon-Nano transgenic mice"
International Journal of Molecular Sciences, 15:19971-19986, 2014 - Mingyue Jin, Masami Yamada, Yoshiyuki Arai, Takeharu Nagai, and Shinji Hirotsune
"Arl3 and LC8 regulate dissociation of dynactin from dynein"
Nature Communications, 5:5295, 2014 - Takahiro Muraoka, Takahiro Endo, Kazuhito V. Tabata, Hiroyuki Noji, Satoru Nagatoishi, Kouhei Tsumoto, Rui Li and Kazushi Kinbara
"Reversible Ion Transportation Switch by a Ligand-Gated Synthetic Supramolecular Ion Channel"
J. Am. Chem. Soc., 136:15584-15595, 2014 - Tomoki Matsuda and Takeharu Nagai
"Quantitative measurement of intracellular protein dynamics using photobleaching or photoactivation of fluorescent proteins"
Microscopy, 63:403-408, 2014 - Mihoko Ui, Kousuke Harima, Toshiaki Takei, Kouhei Tsumoto, Kazuhito V. Tabata, Hiroyuki Noji, Sumire Endo, Kimio Akiyama, Takahiro Muraoka, and Kazushi Kinbara
"Grafting Synthetic Transmembrane Units to the Engineered Low-Toxicity alpha-Hemolysin to Restore Its Hemolytic Activity"
Mol. BioSyst., 10:3199-3206, 2014 - Tatsuya Shima, Takahiro Muraoka, Kazuhito V. Tabata, Hiroyuki Noji and Kazushi Kinbara
"Light-Triggered Vesicle Formation: Important Factors for Generation of Vesicles and Possible Applications"
Pure Appl. Chem., 86:1259-1267, 2014 - Shunichi Kawasaki, Takahiro Muraoka, Haruki Obara, Takerou Ishii, Tsutomu Hamada and Kazushi Kinbara
"Thermodriven Micrometer-Scale Aqueous-Phase Separation of Amphiphilic Oligoethylene Glycol Analogues"
Chem. Asian J., 9:2778-2788, 2014 - Kanemaru K, Sekiya H, Xu M, Satoh K, Kitajima N, Yoshida K, Okubo Y, Sasaki T, Moritoh S, Hasuwa H, Mimura M, Horikawa K, Matsui K, Nagai T, Iino M, and Tanaka KF
"In vivo visualization of subtle, transient and local activity of astrocytes using an ultrasensitive Ca2+ indicator"
Cell Reports, 8:311-318, 2014 - Tatsuya Shima, Takahiro Muraoka, Tsutomu Hamada, Masamune Morita, Masahiro Takagi, Hajime Fukuoka, Yuichi Inoue, Takashi Sagawa, Akihiko Ishijima, Yuki Omata, Takashi Yamashita and Kazushi Kinbara
"Micrometer-Size Vesicle Formation Triggered by UV Light"
Langmuir, 30:7289-7295, 2014 - Tatsuya Shima, Takahiro Muraoka, Norihisa Hoshino, Tomoyuki Akutagawa, Yuka Kobayashi and Kazushi Kinbara
"Thermally Driven Polymorphic Transition Prompting a Naked-Eye-Detectable Bending and Straightening Motion of Single Crystals"
Angew. Chem. Int. Ed., 53:7173-7178, 2014 - Nabanita Sadhukhan, Takahiro Muraoka, Daisuke Abe, Yuji Sasanuma, Dwiky Rendra Graha Subekti and Kazushi Kinbara
"Thermoresponsive Self-assembly and Conformational Changes of Amphiphilic Monodisperse Short Poly(ethylene glycol)s in Water"
Chem. Lett., 43:1055-1057, 2014 - Uehara S, Hanasaki I, Arai Y, Nagai T and Kawano S
"Statistical characterisation of single-stranded DNA motion near glass surface beyond diffusion coefficient"
Micro and Nano Letters, 9:257-260, 2014 - Takahiro Muraoka, Kota Adachi, Rainy Chowdhury and Kazushi Kinbara
"Transetherification on Polyols by Intra- and Intermolecular Nucleophilic Substitutions"
PLoS ONE, 9:e91912, 2014 - Noritaka Fukuda,Tomoki Matsuda and Takeharu Nagai
"Optical Control of the Ca2+ Concentration in a Live Specimen with a Genetically Encoded Ca2+-Releasing Molecular Tool"
ACS Chemical biology, 9:1197-1203, 2014 - Takahiro Muraoka, Nabanita Sadhukhan, Mihoko Ui, Shunichi Kawasaki, Enrikko Hazemi, Kota Adachi, and Kazushi Kinbara
"Thermal-Aggregation Suppression of Proteins by a Structured PEG Analogue: Importance of Denaturation Temperature for Effective Aggregation Suppression"
Biochem. Eng. J., 86C:41-48, 2014 - Kiwamu Takemoto, Tomoki Matsuda, Naoki Sakai, Donald Fu, Masanori Noda, Susumu Uchiyama, Ippei Kotera, Yoshiyuki Arai, Masataka Horiuchi, Kiichi Fukui, Tokiyoshi Ayabe, Fuyuhiko Inagaki, Hiroshi Suzuki and Takeharu Nagai
"SuperNova, a monomeric photosensitizing fluorescent protein for chromophore-assisted light inactivation"
Scientific Reports, 3:2629, 2013 - Tadasu Nozaki, Kazunari Kaizu, Chan-Gi Pack, Sachiko Tamura, Tomomi Tani, Saera Hihara, Takeharu Nagai, Koichi Takahashi and Kazuhiro Maeshima
"Flexible and dynamic nucleosome fiber in living mammalian cells"
Nucleus, 4:41647, 2013 - Masahito Yamanaka, Kenta Saito, Nicholas I. Smith, Satoshi Kawata, Takeharu Nagai and Katsumasa Fujita
"Saturated excitation of fluorescent proteins for subdiffraction-limited imaging of living cells in three dimensions"
Interface Focus, 3:20130007, 2013 - Masami Yamada, Kanako Kumamoto, Shintaro Mikuni, Yoshiyuki Arai, Masataka Kinjo, Takeharu Nagai, Yoshikazu Tsukasaki, Tomonobu M Watanabe, Mitsuru Fukui, Mingyue Jin, Shiori Toba and Shinji Hirotsune
"Rab6a releases LIS1 from a dynein idling complex and activates dynein for retrograde movement"
Nature Communications, 4:2033, 2013 - Shuvendu Biswas, Kazushi Kinbara, Tatsuya Niwa, Hideki Taguchi, Noriyuki Ishii, Sumiyo Watanabe, Kanjiro Miyata, Kazunori Kataoka and Takuzo Aida
"Biomolecular Robotics for Chemomechanically Driven Guest Delivery Duelled by Intracellular ATP""
Nature Chem., 5:613-620, 2013 - Tomoki Matsuda1, Kazuki Horikawa, Kenta Saito & Takeharu Nagai
"Highlighted Ca2+ imaging with a genetically encoded 'caged' indicator"
Sci Rep., 3:1398, 2013 - Jiahui W, Lin Liu, Tomoki Matsuda, Yongxin Zhao, Aleksander Rebane, Mikhail Drobizhev, Yu-Fen Chang, Satoko Araki, Yoshiyuki Arai, Kelsey March, Thomas E. Hughes, Ken Sagou, Takaki Miyata, Takeharu Nagai, Wen-hong Li and Robert E. Campbell
"Improved orange and red Ca2+ indicators and photophysical considerations for optogenetic applications"
ACS Chem. Neurosci., 4:963-972, 2013 - Takahiro Muraoka, Kota Adachi, Mihoko Ui, Shunichi Kawasaki, Nabanita Sadhukhan, Haruki Obara, Hidehito Tochio, Masahiro Shirakawa and Kazushi Kinbara
"A Structured Monodisperse PEG for the Effective Suppression of Protein Aggregation"
Angew. Chem. Int. Ed., 52:2430-2434, 2013 - Hiofan Hoi, Tomoki Matsuda, Takeharu Nagai, and Robert E. Campbell
"Highlightable Ca2+ Indicators for Live Cell Imaging."
J Am Chem Soc., 135:46-49, 2013 - Hihara S, Pack CG, Hanafusa T, Kaizu K, Tani T, Takemoto S, Yoshimi T, Sako Y, Yokota H, Imamoto N, Kinjo M, Takahashi K, Nagai T and Maeshima K.
"Local Nucleosome Dynamics Facilitate Chromatin Accessibility in Living Mammalian Cells ."
Cell Rep., 2:1645-1656, 2012 - Saito k, Chang Yu-Fen, Horikawa K, Hatsugai N, Higuchi Y, Hashida M, Yoshida Y, Matsuda T, Arai Y, and Nagai T.
"A luminescent protein for high-speed single-cell and whole-body imaging."
Nat Commun., 3:1262, 2012 - Kominami K, Nagai T, Sawasaki T, Tsujimura Y,Yashima K, Sunaga Y, Tsuchimochi M, Nishimura J, Chiba K, Nakabayashi J, Koyamada K, Endo Y, Yokota H, Miyawaki A, Manabe N, Sakamaki K.
"In vivo imaging of hierarchical spatiotemporal activation of caspase-8 during apoptosis."
PLoS ONE, 7:e50218, 2012 - Iwano M, Ngo QA, Entani T, Shiba H, Nagai T, Miyawaki A, Isogai A, Grossniklaus U, Takayama S.
"Cytoplasmic Ca2+ changes dynamically during the interaction of the pollen tube with synergid cells."
Development., 139:4202-4209, 2012 - Takahiro Muraoka, Tatsuya Shima, Tsutomu Hamada, Masamune Morita, Masahiro Takagi, Kazuhito V. Tabata, Hiroyuki Noji and Kazushi Kinbara
"Ion Permeation by a Folded Multiblock Amphiphilic Oligomer Achieved by Hierarchical Construction of Self-Assembled Nanopores"
Journal of the American Chemical Society, 134:19788-19794, 2012 - Kominami K, Nakabayashi J, Nagai T, Tsujimura Y, Chiba K, Kimura H, Miyawaki A, Sawasaki T, Yokota H, Manabe N, Sakamaki K.
"The molecular mechanism of apoptosis upon caspase-8 activation: quantitative experimental validation of a mathematical model."
Biochim Biophys Acta., 1823:1825-1840, 2012 - Mihoko Ui, Yoshikazu Tanaka and Kazushi Kinbara
"Amplification of Light-induced Molecular-Shape Change by Supramolecular Machines"
J. Photopolym. Sci. Technol., 25:655-658, 2012 - Yu-Fen Chang, Yoshiyuki Arai, Takeharu Nagai
"Optogenetic activation during detector 'dead time' enables compatible real-time fluorescence imaging."
Neuroscience Research, 73:341-347, 2012 - Hatsugai N, Perez Koldenkova V, Imamura H, Noji H, Nagai T.
"Changes in Cytosolic ATP Levels and Intracellular Morphology during Bacteria-Induced Hypersensitive Cell Death as Revealed by Real-Time Fluorescence Microscopy Imaging."
Plant Cell Physiol., 53:1768-1775, 2012 - Takeshi Tokunaga, Shigeyuki Namiki, Katsuhiro Yamada, Takahiro Imaishi, Hiroshi Nonaka, Kenzo Hirose and Shinsuke Sando
"Cell Surface-Anchored Fluorescent Aptamer Sensor Enables Imaging of Chemical Transmitter Dynamics"
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134:9561-9564, 2012 - Keiichi Ohtsuka, Shinobu Sato, Yusuke Sato, Kojiro Sota, Shinsuke Ohzawa, Tomoki Matsuda, Kiwamu Takemoto, Nobutoki Takamune, Bernard Juskowiak, Takeharu Nagai and Shigeori Takenaka
"Fluorescence imaging of potassium ions in living cells using a fluorescent probe based on a thrombin binding aptamer-peptide conjugate."
Chem. Commun., 48:4740-4742, 2012 - Mihoko Ui, Yoshikazu Tanaka, Yasuyuki Araki, Takehiko Wada, Toshiaki Takei, Kouhei Tsumoto and Kazushi Kinbara
"Application of Photoactive Yellow Protein as a Photoresponsive Module for Controlling Hemolytic Activity of Staphylococcal a-Hemolysin"
Chemical Communications, 48:4737-4739, 2012 - Kwon HJ, Ohmiya Y, Honma KI, Honma S, Nagai T, Saito K, Yasuda K
"Synchronized ATP oscillations have a critical role in prechondrogenic condensation during chondrogenesis."
Cell Death Dis., 3:e278, 2012 - Tatsuya Nishihara, Hiroshi Nonaka, Tatsuya Naganuma, Kazuhiro Ichikawa and Shinsuke Sando
"Mouse Lactate Dehydrogenase X: A Promising Magnetic Resonance Reporter Protein Using Hyperpolarized Pyruvic Acid Derivative Y"
Chemical Science, 3:800-806, 2012 - Hisatsugu Yamada, Keigo Mizusawa, Ryuji Igarashi, Hidehito Tochio, Masahiro Shirakawa, Yasuhiko Tabata, Yu Kimura, Teruyuki Kondo, Yasuhiro Aoyama and Shinsuke Sando
"Substrate/Product-Targeted NMR Monitoring of Pyrimidine Catabolism and Its Inhibition by a Clinical Drug"
ACS Chemical Biology, 7:535-542, 2012 - Kenta Saito, Yoshiyuki Arai, Jize Zhang, Kentaro Kobayashi, Tomomi Tani, Takeharu Nagai
"Conjugation of both on-axis and off-axis light in Nipkow disk confocal microscope to increase availability of incoherent light source."
Cell Structure and Function, 36:237-246, 2011 - Yoshiyuki Yamada, Takayuki Michikawa, Mitsuhiro Hashimoto, Kazuki Horikawa, Takeharu Nagai, Atsushi Miyawaki, Michael Häusser and Katsuhiko Mikoshiba
"Quantitative comparison of genetically encoded Ca2+ indicators in cortical pyramidal cells and cerebellar Purkinje cells."
Front Cell Neurosci, 5(18):40918, 2011 - Yongxin Zhao, Satoko Araki, Jiahui Wu, Takayuki Teramoto, Yu-Fen Chang, Masahiro Nakano, Ahmed S. Abdelfattah, Manabi Fujiwara, Takeshi Ishihara, Takeharu Nagai, Robert E. Campbell
"An expanded palette of genetically encoded Ca2+ indicators."
Science, 333:1888-1891, 2011 - Mami Nomura, Takeharu Nagai, Yoshie Harada and Tomomi Tani
"Facilitated intracellular transport of TrkA by an interaction with nerve growth factor."
Dev. Neurobiol., 71(1):634-649, 2011 - Yang L, Matsuda T, Raviraj V, Nagai T. and Soon L L.
"Imaging the Dynamics of Intracellular Protein Translocation by Photoconversion of Phamret-Cybr/ROM."
Journal of Microscopy, 242(3):250-261, 2011 - Kiwamu Takemoto, Tomoki Matsuda, Mark McDougall, Dieter H. Klaubert, Akira Hasegawa, Georgyi V. Los, Keith V. Wood, Atsushi Miyawaki and Takeharu Nagai
"Chromophore-assisted light inactivation of HaloTag fusion proteins labeled with eosin in living cells"
ACS Chem. Biol., 6(5):401–406, 2011