研究業績／原著論文

A01班

A01-1 野地班

• Ryunosuke Hayashi, Kazuo Kasaki, Shuichi Nakamura, Seishi Kudo, Yuichi Inoue, Hiroyuki Noji and Kumiko Hayashi
  "Giant acceleration of diffusion observed in a single-molecule experiment on F 1-ATPase"
  Physical Review Letters, 114:248101, 2015
• Jun-ichi Kishikawa, Akihiko Seino, Atsuko Nakanishi, Naciye Esma Tirtom, Hiroyuki Noji, Ken Yokoyama and Kumiko Hayashi
  "F-subunit reinforces torque generation in V-ATPase"
  European Biophysics Journal, 43:415-422, 2014
• Taro Ichimura, Liang-da Chiu, Katsumasa Fujita, Satoshi Kawata, Tomonobu M. Watanabe, Toshio Yanagida, Hideaki Fujita
  "Visualizing Cell State Transition Using Raman Spectroscopy"
  PLoS One, 9:e84478, 2014
• Sayaka Higuchi, Tomonobu M. Watanabe, Keiko Kawauchi, Taro Ichimura and Hideaki Fujita
  "Culturing of mouse and human cells on soft substrates promote the expression of stem cell markers."
  Journal of Bioscience and Bioengineering, S1389-1723(13):434-439, 2013
• Taka-aki Yano, Taro Ichimura, Shota Kuwahara, Fekhra H’Dhili, Kazumasa Uetsuki, Yoshito Okuno, Prabhat Verma, and Satoshi Kawata
  "Tip-enhanced nano-Raman analytical imaging of locally induced strain distribution in carbon nanotubes"
  Nature Communications, 4:2592, 2013
• Tomonobu M. Watanabe, Katsumi Imada, Keiko Yoshizawa, Masayoshi Nishijima, Chiaki Kato, Fumiyoshi Abe, Takamitsu J. Morikawa, Miki Kinoshita, Hideaki Fujita and Toshio Yanagida
  "Glycine Insertion Makes Yellow Fluorescent Protein Sensitive to Hydrostatic Pressure."
  PLoS PNE, 8(8):e73212, 2013
• Tomonobu M. Watanabe, Fumihiko Fujii, Takashi Jin, Eiji Umemoto, Masayuki Miyasaka, Hideaki Fujita and Toshio Yanagida
  "Four-Dimensional Spatial Nanometry of Single Particles in Living Cells Using Polarized Quantum Rods."
  Biophysical Journal, 105(3):555-564, 2013
• Masami Yamada, Kanako Kumamoto, Shintaro Mikuni, Yoshiyuki Arai, Masataka Kinjo, Takeharu Nagai, Yoshikazu Tsukasaki, Tomonobu M Watanabe, Mitsuru Fukui, Mingyue Jin, Shiori Toba and Shinji Hirotsune
  "Rab6a releases LIS1 from a dynein idling complex and activates dynein for retrograde movement."
  Nature Communications, 4:2033, 2013
• 渡邉朋信, 神隆, 市村垂生
  "生体分子動態のナノイメージング"
  光アライアンス, 24:15-20, 2013
• Jun Yu, Yuika Saito, Taro Ichimura, Satoshi Kawata and Prabhat Verma
  "Far-field free tapping-mode tip-enhanced Raman microscopy."
  Applied Physics Letters, 102(12):123110, 2013
• Togo Shimozawa, Kazuo Yamagata, Takefumi Kondo, Shigeo Hayashi, Atsunori Shitamukai, Daijiro Konno, Fumio Matsuzaki, Jun Takayama, Shuichi Onami, Hiroshi Nakayama, Yasuhito Kosugi, Tomonobu M. Watanabe, Katsumasa Fujita, Yuko Mimori-Kiyosue
  "Improving spinning disk confocal microscopy by preventing pinhole cross-talk for intravital imaging."
  PNAS, 110(9):3399-3404, 2013
• Naciye Esma Tirtom, Daichi Okuno, Masahiro Nakano, Ken Yokoyama and Hiroyuki Noji
  "Mechanical Modulation of ATP-binding Affinity of V1-ATPase."
  The Journal of Biological Chemistry, 288:619-623, 2013
• Sawako Enoki, Ryota Iino, Nobuhiro Morone, Kunihiro Kaihatsu, Shouichi Sakakihara, Nobuo Kato and Hiroyuki Noji
  "Label-free single-particle imaging of the influenza virus by objective-type total internal reflection dark-field microscopy"
  PLoS ONE, 7:e49208, 1-7, 2012
• Takahiro Muraoka, Tatsuya Shima, Tsutomu Hamada, Masamune Morita, Masahiro Takagi, Kazuhito V. Tabata, Hiroyuki Noji, and Kazushi Kinbara
  "Ion Permeation by a Folded Multiblock Amphiphilic Oligomer Achieved by Hierarchical Construction of Self-Assembled Nanopores"
  Journal of The American Chemical Society, 134:19788-19794, 2012
• Huijuan You, Ryota Iino, Rikiya Watanabe and Hiroyuki Noji
  "Winding single-molecule double-stranded DNA on a nanometer-sized reel."
  Nucleic Acids Research, 40(19):e151, 2012
• Mizue Tanigawara, Kazuhito V. Tabata, Yuko Ito, Jotaro Ito, Rikiya Watanabe, Hiroshi Ueno, Mitsunori Ikeguchi and Hiroyuki Noji
  "Role of the DELSEED Loop in Torque Transmission of F1-ATPase"
  Biophysical Journal, 103:970-978, 2012
• Tomonobu M. Watanabe, Yoshikazu Tsukasaki, Hideaki Fujita, Taro Ichimura, Tatsuya Saitoh, Shizuo Akira, and Toshio Yanagida
  "Distinct modulated pupil function system for real-time imaging of living cells."
  PlosOne, 7:e44028, 2012
• Noriyuki Hatsugai, Vadim Perez Koldenkova, Hiromi Imamura, Hiroyuki Noji and Takeharu Nagai
  "Changes in Cytosolic ATP Levels and Intracellular Morphology during Bacteria-Induced Hypersensitive Cell Death as Revealed by Real-Time Fluorescence Microscopy Imaging"
  Plant and Cell Physiology, 53:1768-1775, 2012
• Qiang Ma, Yuko Nakane, Yuki Mori, Miyuki Hasegawa, Yoshichika Yoshioka, Tomonobu M.Watanabe, Kohsuke Gonda, Noriaki Ohuchi and Takashi Jin.
  "Multilayered, core/shell nanoprobes based on magnetic ferric oxide particles and quantum dots for multimodality imaging of breast cancer tumors."
  Biomaterials, 33:8486-94, 2012
• Naciye Esma Uner, Yoshihiro Nishikawa, Daichi Okuno, Masahiro Nakano, Ken Yokoyama and Hiroyuki Noji
  "Single-molecule analysis of inhibitory pausing states of V1-ATPase"
  The Journal of Biological Chemistry, 287:28327-28335, 2012
• Soo Hyeon Kim , Shino Iwai , Suguru Araki , Shouichi Sakakihara , Ryota Iino and Hiroyuki Noji
  "Large-scale femtoliter droplet array for digital counting of single biomolecules"
  Lab on a Chip, 12:4986-4991, 2012
• Hayashi Yamamoto, Soichiro Kakuta, Tomonobu M. Watanabe, Akira Kitamura, Takayuki Sekito, Chika Kondo-Kakuta, Rie Ichikawa, Masataka Kinjo, and Yoshinori Ohsumi
  "Atg9 vesicles are an important membrane source during early steps of autophagosome formation."
  Journal of Cell Biology, 198:219-233, 2012
• Taro Ichimura, Hideaki Fujita, Keiko Yoshizawa and Tomonobu M. Watanabe
  "Engineering strain-sensitive yellow fluorescent protein"
  Chemical Communications, 48:7871-7873, 2012
• Ryota Iino, Kohei Hayama, Hiromi Amezawa, Shouichi Sakakihara, Soo Hyeon Kim, Yoshimi Matsumono, Kunihiko Nishino, Akihito Yamaguchi and Hiroyuki Noji
  "A single-cell drug efflux assay in bacteria by using a directly accessible femtoliter droplet array"
  Lab on a Chip, 12:3923-3929, 2012
• Takaaki Yano, Taro Ichimura, Shota Kuwahara, Prabhat Verma and Satoshi Kawata
  "Subnanometric stabilization of plasmon-enhanced optical microscopy"
  Nanotechnology, 23:205503, 2012
• Yoshihito Komoriya, Takayuki Ariga, Ryota Iino, Hiromi Imamura, Daichi Okuno and Hiroyuki Noji
  "Principal Role of the Arginine Finger in Rotary Catalysis of F1-ATPase"
  JOURNAL OF BIOLOGICAL CHEMISTRY, 287:15134-15142, 2012
• Shigehiko Hayashi, Hiroshi Ueno, Shaikh, Abdul Rajjak, Myco Umemura, Motoshi Kamiya, Yuko Ito, Mitsunori Ikeguchi, Yoshihito Komoriya, Ryota Iino and Hiroyuki Noji
  "Molecular Mechanism of ATP Hydrolysis in F-1-ATPase Revealed by Molecular Simulations and Single-Molecule Observations"
  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134:8447-8454, 2012
• Tomonobu Watanabe, Sayaka Higuchi, Keiko Kawauchi, Yoshikazu Tsukasaki, Taro Ichimura and Hideaki Fujita
  "Chromatin plasticity as a differentiation index during muscle differentiation of C2C12 myoblasts."
  Biochem Biophys Res Commun, 418:742, 2012
• Kiyotaka Sasagawa, Keisuke Ando, Takuma Kobayashi, Toshihiko Noda, Takashi Tokuda, Soo Hyeon Kim, Ryota Iino, Hiroyuki Noji, and Jun Ohta
  "Complementary Metal-Oxide-Semiconductor Image Sensor with Microchamber Array for Fluorescent Bead Counting"
  Japanese Journal of Applied Physics, 51:02BL01, 2012
• Rikiya Watanabe, Daichi Okuno, Shouichi Sakakihara, Katsuya Shimabukuro, Ryota Iino, Masasuke Yoshida & Hiroyuki Noji
  "Mechanical modulation of catalytic power on F1-ATPase"
  Nature Chemical Biology, 8:86–92, 2011
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A01-2 永井班

• Tetsuichi Wazawa, Nobuyuki Morimoto, Takeharu Nagai and Makoto Suzuki
  "Rotational motion of rhodamine 6G tethered to actin through oligo(ethylene glycol) linkers studied by frequency-domain fluorescence anisotropy"
  Biophysics and Physicobiology, 12(2015):87-102, 2015
• Itsuo Hanasaki, Satoshi Uehara, Yoshiyuki Arai, Takeharu Nagai and Satoyuki Kawano
  "Threshold-free evaluation of near-surface diffusion and adsorption-dominated motion from single-molecule tracking data of single-stranded DNA through TIRF"
  Japanese Journal of Applied Physics, 54:12, 2015
• Koji L. Ode and Hiroki R. Ueda
  "Seeing the forest and trees: whole-body and whole-brain imaging for circadian biology"
  Diabetes, Obesity and Metabolism, 17 Suppl 1:47-54, 2015
• Karam Kim, Gurpreet Lakhanpal, Hsiangmin E. Lu, Mustafa Khan, Akio Suzuki, Mariko Kato Hayashi, Radhakrishnan Narayanan, Thomas T. Luyben, Tomoki Matsuda, Takeharu Nagai, Thomas A. Blanpied, Yasunori Hayashi and Kenichi Okamoto.
  "A temporary gating mechanism of actin remodeling during sy 1 naptic plasticity consists of the interplay between the kinase and structural functions of CaMKII"
  Neuron, 87(4):813-826, 2015
• Vadim Pérez Koldenkova, Tomoki Matsuda and Takeharu Nagai
  "MagIC, a genetically encoded fluorescent indicator for monitoring cellular Mg2+ using a non-FRET ratiometric imaging approach"
  Journal of Biomedical Optics, 20(10):101203, 2015
• Masahito Yamanaka, Kenta Saito, Nicholas I. Smith, Yoshiyuki Arai, Kumiko Uegaki, Yasuo Yonemaru, Kentaro Mochizuki, Satoshi Kawata, Takeharu Nagai and Katsumasa Fujita
  "Visible-wavelength two-photon excitation microscopy for fluorescent protein imaging"
  Journal of Biomedical Optics, 20(10):101202, 2015
• Shin-nosuke Uno, Dhermendra K. Tiwari, Mako Kamiya, Yoshiyuki Arai, Takeharu Nagai and Yasuteru Urano
  "A guide to use photocontrollable fluorescent proteins and synthetic smart fluorophores for nanoscopy."
  Microscopy, 0:1-15, 2015
• 中野雅裕、永井健治
  "肉眼でも観察できる！　３色（水色, 黄緑色, 橙色）の高光度発光タンパク質"
  O plus E, 428:505-506, 2015
• Kenta Saito and Takeharu Nagai
  "Recent progress in luminescent proteins development"
  Current Opinion In Chemical Biology, 27:46-51, 2015
• Akihiro Nezu, Takao Morita, Yosuke Tojyo,Takeharu Nagai and Akihiko Tanimura
  "Partial agonistic effects of pilocarpine on Ca2+ responses and salivary secretion in the submandibular glands of live animals"
  Experimental Physiology, 100:640-651, 2015
• Yoshiyuki Arai, Takayuki Yamamoto, Takeo Minamikawa, Tetsuro Takamatsu and Takeharu Nagai
  "Spectral fingerprinting of individual cells visualized by cavity-reflection-enhanced light-absorption microscopy"
  PLoS ONE, 10:125733, 2015
• Dhermendra K Tiwari, Yoshiyuki Arai, Masahito Yamanaka, Tomoki Matsuda, Masakazu Agetsuma, Masahiro Nakano, Katsumasa Fujita and Takeharu Nagai
  "A fast- and positively photoswitchable fluorescent protein for ultralow-laser-power RESOLFT nanoscopy"
  Nature Methods, 12:515-518, 2015
• Akira Takai, Masahiro Nakano, Kenta Saito, Remi Haruno, Tomonobu M. Watanabe, Tatsuya Ohyanagi, Takashi Jin, Yasushi Okada and Takeharu Nagai
  "Expanded palette of Nano-lantern for real-time muliti-color luminescence imaging"
  Proc. Natl. Acad. Sci. USA, 112:4352-4356, 2015
• Takeharu Nagai
  "Real time imaging of biological phenomena with super-duper luminescent proteins"
  CYTOLOGIA, 80:1-2, 2015
• Kazunori Sugiura,Takeharu Nagai,Masahiro Nakano,Hiroshi Ichinose,Takakazu Nakabayashi,Nobuhiro Ohta and Toru Hisabori
  "Redox sensor proteins for highly sensitive direct imaging of intracellular redox state"
  Biochemical and Biophysical Research Communications, 457(3):242-248, 2015
• Hiroyuki Ichijo, Michito Hamada, Satoru Takahashi, Makoto Kobayashi, Takeharu Nagai, Tomoko Toyama and Masahumi Kawaguchi
  "Lateralization, maturation, and anteroposterior topography in the lateral habenula revealed by ZIF268/EGR1 immunoreactivity and labeling history of neuronal activity."
  Neuroscience Reserach, 95:27-37, 2015
• Takahiro Muraoka, Nabanita Sadhukhan, Rui Li and Kazushi Kinbara
  "Development of Self-Assembling Alternating Amphiphilic Compounds"
  J. Photopolym. Sci. Tec., 27:557-560, 2014
• Shinji Yoshiyama, Zhenyi Chen, Tsuyoshi Okagaki, Kazuhiro Kohama, Ritsuko Nasu-Kawaharada, Takashi Izumi, Noriyasu Ohshima, Takeharu Nagai, and Akio Nakamura
  "Nicotine exposure alters human vascular smooth muscle cell phenotype from a contractile to a synthetic type"
  Atherosclerosis, 237:464-470, 2014
• Yoshiyuki Arai and Takeharu Nagai
  "Real-Time Chemiluminescence Imaging Using Nano-Lantern Probes"
  Current Protocols in Chemical Biology, 6:221-236, 2014
• 永井健治
  "回折限界を超えた超解像蛍光顕微鏡"
  化学, 69:21-26, 2014
• Takeharu Nagai, Kazuki Horikawa,Kenta Saito and Tomiki Matsuda
  "Genetically encoded Ca2+ indicators; expanded affinity range, color hue and compatibility with optogenetics"
  Frontiers in Neuroscience, 7, 2014
• Yusuke Oshima, Takaeshi Imamura, Atsuko Shintani, Hiroko Kajiura-Kobayashi, Terumasa Hibi, Takeharu Nagai, shigenori Nonaka and Tomomi Nemoto
  "Ultrasensitive imaging of Ca2+ dynamics in pancreatic acinar cells of Yellow Cameleon-Nano transgenic mice"
  International Journal of Molecular Sciences, 15:19971-19986, 2014
• Mingyue Jin, Masami Yamada, Yoshiyuki Arai, Takeharu Nagai, and Shinji Hirotsune
  "Arl3 and LC8 regulate dissociation of dynactin from dynein"
  Nature Communications, 5:5295, 2014
• Takahiro Muraoka, Takahiro Endo, Kazuhito V. Tabata, Hiroyuki Noji, Satoru Nagatoishi, Kouhei Tsumoto, Rui Li and Kazushi Kinbara
  "Reversible Ion Transportation Switch by a Ligand-Gated Synthetic Supramolecular Ion Channel"
  J. Am. Chem. Soc., 136:15584-15595, 2014
• 齋藤健太、永井健治
  "高輝度化学発光タンパク質Nano-lanternの開発"
  化学と生物, 52:646-650, 2014
• Tomoki Matsuda and Takeharu Nagai
  "Quantitative measurement of intracellular protein dynamics using photobleaching or photoactivation of fluorescent proteins"
  Microscopy, 63:403-408, 2014
• Mihoko Ui, Kousuke Harima, Toshiaki Takei, Kouhei Tsumoto, Kazuhito V. Tabata, Hiroyuki Noji, Sumire Endo, Kimio Akiyama, Takahiro Muraoka, and Kazushi Kinbara
  "Grafting Synthetic Transmembrane Units to the Engineered Low-Toxicity alpha-Hemolysin to Restore Its Hemolytic Activity"
  Mol. BioSyst., 10:3199-3206, 2014
• Tatsuya Shima, Takahiro Muraoka, Kazuhito V. Tabata, Hiroyuki Noji and Kazushi Kinbara
  "Light-Triggered Vesicle Formation: Important Factors for Generation of Vesicles and Possible Applications"
  Pure Appl. Chem., 86:1259-1267, 2014
• Shunichi Kawasaki, Takahiro Muraoka, Haruki Obara, Takerou Ishii, Tsutomu Hamada and Kazushi Kinbara
  "Thermodriven Micrometer-Scale Aqueous-Phase Separation of Amphiphilic Oligoethylene Glycol Analogues"
  Chem. Asian J., 9:2778-2788, 2014
• Kanemaru K, Sekiya H, Xu M, Satoh K, Kitajima N, Yoshida K, Okubo Y, Sasaki T, Moritoh S, Hasuwa H, Mimura M, Horikawa K, Matsui K, Nagai T, Iino M, and Tanaka KF
  "In vivo visualization of subtle, transient and local activity of astrocytes using an ultrasensitive Ca2+ indicator"
  Cell Reports, 8:311-318, 2014
• Tatsuya Shima, Takahiro Muraoka, Tsutomu Hamada, Masamune Morita, Masahiro Takagi, Hajime Fukuoka, Yuichi Inoue, Takashi Sagawa, Akihiko Ishijima, Yuki Omata, Takashi Yamashita and Kazushi Kinbara
  "Micrometer-Size Vesicle Formation Triggered by UV Light"
  Langmuir, 30:7289-7295, 2014
• Tatsuya Shima, Takahiro Muraoka, Norihisa Hoshino, Tomoyuki Akutagawa, Yuka Kobayashi and Kazushi Kinbara
  "Thermally Driven Polymorphic Transition Prompting a Naked-Eye-Detectable Bending and Straightening Motion of Single Crystals"
  Angew. Chem. Int. Ed., 53:7173-7178, 2014
• 新井由之、永井健治
  "CCDカメラのデッドタイムを利用した光刺激法が可能にする蛍光・化学発光イメージングとオプトジェネティクスの高時間分解併用"
  生化学, 86:167-173, 2014
• Nabanita Sadhukhan, Takahiro Muraoka, Daisuke Abe, Yuji Sasanuma, Dwiky Rendra Graha Subekti and Kazushi Kinbara
  "Thermoresponsive Self-assembly and Conformational Changes of Amphiphilic Monodisperse Short Poly(ethylene glycol)s in Water"
  Chem. Lett., 43:1055-1057, 2014
• 松田知己、永井健治
  "光スイッチング機能プローブで挑む細胞の個性"
  生体の科学, 65:101-106, 2014
• Uehara S, Hanasaki I, Arai Y, Nagai T and Kawano S
  "Statistical characterisation of single-stranded DNA motion near glass surface beyond diffusion coefficient"
  Micro and Nano Letters, 9:257-260, 2014
• 永井健治
  "今のめり込み術のマルチ効能"
  生物物理, 54:75, 2014
• Takahiro Muraoka, Kota Adachi, Rainy Chowdhury and Kazushi Kinbara
  "Transetherification on Polyols by Intra- and Intermolecular Nucleophilic Substitutions"
  PLoS ONE, 9:e91912, 2014
• Noritaka Fukuda,Tomoki Matsuda and Takeharu Nagai
  "Optical Control of the Ca2+ Concentration in a Live Specimen with a Genetically Encoded Ca2+-Releasing Molecular Tool"
  ACS Chemical biology, 9:1197-1203, 2014
• Takahiro Muraoka, Nabanita Sadhukhan, Mihoko Ui, Shunichi Kawasaki, Enrikko Hazemi, Kota Adachi, and Kazushi Kinbara
  "Thermal-Aggregation Suppression of Proteins by a Structured PEG Analogue: Importance of Denaturation Temperature for Effective Aggregation Suppression"
  Biochem. Eng. J., 86C:41-48, 2014
• Kiwamu Takemoto, Tomoki Matsuda, Naoki Sakai, Donald Fu, Masanori Noda, Susumu Uchiyama, Ippei Kotera, Yoshiyuki Arai, Masataka Horiuchi, Kiichi Fukui, Tokiyoshi Ayabe, Fuyuhiko Inagaki, Hiroshi Suzuki and Takeharu Nagai
  "SuperNova, a monomeric photosensitizing fluorescent protein for chromophore-assisted light inactivation"
  Scientific Reports, 3:2629, 2013
• Tadasu Nozaki, Kazunari Kaizu, Chan-Gi Pack, Sachiko Tamura, Tomomi Tani, Saera Hihara, Takeharu Nagai, Koichi Takahashi and Kazuhiro Maeshima
  "Flexible and dynamic nucleosome fiber in living mammalian cells"
  Nucleus, 4:41647, 2013
• Masahito Yamanaka, Kenta Saito, Nicholas I. Smith, Satoshi Kawata, Takeharu Nagai and Katsumasa Fujita
  "Saturated excitation of fluorescent proteins for subdiffraction-limited imaging of living cells in three dimensions"
  Interface Focus, 3:20130007, 2013
• Masami Yamada, Kanako Kumamoto, Shintaro Mikuni, Yoshiyuki Arai, Masataka Kinjo, Takeharu Nagai, Yoshikazu Tsukasaki, Tomonobu M Watanabe, Mitsuru Fukui, Mingyue Jin, Shiori Toba and Shinji Hirotsune
  "Rab6a releases LIS1 from a dynein idling complex and activates dynein for retrograde movement"
  Nature Communications, 4:2033, 2013
• Shuvendu Biswas, Kazushi Kinbara, Tatsuya Niwa, Hideki Taguchi, Noriyuki Ishii, Sumiyo Watanabe, Kanjiro Miyata, Kazunori Kataoka and Takuzo Aida
  "Biomolecular Robotics for Chemomechanically Driven Guest Delivery Duelled by Intracellular ATP""
  Nature Chem., 5:613-620, 2013
• Tomoki Matsuda1, Kazuki Horikawa, Kenta Saito & Takeharu Nagai
  "Highlighted Ca2+ imaging with a genetically encoded 'caged' indicator"
  Sci Rep., 3:1398, 2013
• Jiahui W, Lin Liu, Tomoki Matsuda, Yongxin Zhao, Aleksander Rebane, Mikhail Drobizhev, Yu-Fen Chang, Satoko Araki, Yoshiyuki Arai, Kelsey March, Thomas E. Hughes, Ken Sagou, Takaki Miyata, Takeharu Nagai, Wen-hong Li and Robert E. Campbell
  "Improved orange and red Ca2+ indicators and photophysical considerations for optogenetic applications"
  ACS Chem. Neurosci., 4:963-972, 2013
• Takahiro Muraoka, Kota Adachi, Mihoko Ui, Shunichi Kawasaki, Nabanita Sadhukhan, Haruki Obara, Hidehito Tochio, Masahiro Shirakawa and Kazushi Kinbara
  "A Structured Monodisperse PEG for the Effective Suppression of Protein Aggregation"
  Angew. Chem. Int. Ed., 52:2430-2434, 2013
• Hiofan Hoi, Tomoki Matsuda, Takeharu Nagai, and Robert E. Campbell
  "Highlightable Ca2+ Indicators for Live Cell Imaging."
  J Am Chem Soc., 135:46-49, 2013
• Hihara S, Pack CG, Hanafusa T, Kaizu K, Tani T, Takemoto S, Yoshimi T, Sako Y, Yokota H, Imamoto N, Kinjo M, Takahashi K, Nagai T and Maeshima K.
  "Local Nucleosome Dynamics Facilitate Chromatin Accessibility in Living Mammalian Cells ."
  Cell Rep., 2:1645-1656, 2012
• Saito k, Chang Yu-Fen, Horikawa K, Hatsugai N, Higuchi Y, Hashida M, Yoshida Y, Matsuda T, Arai Y, and Nagai T.
  "A luminescent protein for high-speed single-cell and whole-body imaging."
  Nat Commun., 3:1262, 2012
• Kominami K, Nagai T, Sawasaki T, Tsujimura Y,Yashima K, Sunaga Y, Tsuchimochi M, Nishimura J, Chiba K, Nakabayashi J, Koyamada K, Endo Y, Yokota H, Miyawaki A, Manabe N, Sakamaki K.
  "In vivo imaging of hierarchical spatiotemporal activation of caspase-8 during apoptosis."
  PLoS ONE, 7:e50218, 2012
• Iwano M, Ngo QA, Entani T, Shiba H, Nagai T, Miyawaki A, Isogai A, Grossniklaus U, Takayama S.
  "Cytoplasmic Ca2+ changes dynamically during the interaction of the pollen tube with synergid cells."
  Development., 139:4202-4209, 2012
• Takahiro Muraoka, Tatsuya Shima, Tsutomu Hamada, Masamune Morita, Masahiro Takagi, Kazuhito V. Tabata, Hiroyuki Noji and Kazushi Kinbara
  "Ion Permeation by a Folded Multiblock Amphiphilic Oligomer Achieved by Hierarchical Construction of Self-Assembled Nanopores"
  Journal of the American Chemical Society, 134:19788-19794, 2012
• Kominami K, Nakabayashi J, Nagai T, Tsujimura Y, Chiba K, Kimura H, Miyawaki A, Sawasaki T, Yokota H, Manabe N, Sakamaki K.
  "The molecular mechanism of apoptosis upon caspase-8 activation: quantitative experimental validation of a mathematical model."
  Biochim Biophys Acta., 1823:1825-1840, 2012
• Mihoko Ui, Yoshikazu Tanaka and Kazushi Kinbara
  "Amplification of Light-induced Molecular-Shape Change by Supramolecular Machines"
  J. Photopolym. Sci. Technol., 25:655-658, 2012
• Yu-Fen Chang, Yoshiyuki Arai, Takeharu Nagai
  "Optogenetic activation during detector 'dead time' enables compatible real-time fluorescence imaging."
  Neuroscience Research, 73:341-347, 2012
• Hatsugai N, Perez Koldenkova V, Imamura H, Noji H, Nagai T.
  "Changes in Cytosolic ATP Levels and Intracellular Morphology during Bacteria-Induced Hypersensitive Cell Death as Revealed by Real-Time Fluorescence Microscopy Imaging."
  Plant Cell Physiol., 53:1768-1775, 2012
• Takeshi Tokunaga, Shigeyuki Namiki, Katsuhiro Yamada, Takahiro Imaishi, Hiroshi Nonaka, Kenzo Hirose and Shinsuke Sando
  "Cell Surface-Anchored Fluorescent Aptamer Sensor Enables Imaging of Chemical Transmitter Dynamics"
  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134:9561-9564, 2012
• Keiichi Ohtsuka, Shinobu Sato, Yusuke Sato, Kojiro Sota, Shinsuke Ohzawa, Tomoki Matsuda, Kiwamu Takemoto, Nobutoki Takamune, Bernard Juskowiak, Takeharu Nagai and Shigeori Takenaka
  "Fluorescence imaging of potassium ions in living cells using a fluorescent probe based on a thrombin binding aptamer-peptide conjugate."
  Chem. Commun., 48:4740-4742, 2012
• Mihoko Ui, Yoshikazu Tanaka, Yasuyuki Araki, Takehiko Wada, Toshiaki Takei, Kouhei Tsumoto and Kazushi Kinbara
  "Application of Photoactive Yellow Protein as a Photoresponsive Module for Controlling Hemolytic Activity of Staphylococcal a-Hemolysin"
  Chemical Communications, 48:4737-4739, 2012
• Kwon HJ, Ohmiya Y, Honma KI, Honma S, Nagai T, Saito K, Yasuda K
  "Synchronized ATP oscillations have a critical role in prechondrogenic condensation during chondrogenesis."
  Cell Death Dis., 3:e278, 2012
• Tatsuya Nishihara, Hiroshi Nonaka, Tatsuya Naganuma, Kazuhiro Ichikawa and Shinsuke Sando
  "Mouse Lactate Dehydrogenase X: A Promising Magnetic Resonance Reporter Protein Using Hyperpolarized Pyruvic Acid Derivative Y"
  Chemical Science, 3:800-806, 2012
• 齋藤健太，永井健治
  "生物発光を利用した細胞内カルシウムイメージング"
  生物物理, 49:30-31, 2012
• Hisatsugu Yamada, Keigo Mizusawa, Ryuji Igarashi, Hidehito Tochio, Masahiro Shirakawa, Yasuhiko Tabata, Yu Kimura, Teruyuki Kondo, Yasuhiro Aoyama and Shinsuke Sando
  "Substrate/Product-Targeted NMR Monitoring of Pyrimidine Catabolism and Its Inhibition by a Clinical Drug"
  ACS Chemical Biology, 7:535-542, 2012
• Kenta Saito, Yoshiyuki Arai, Jize Zhang, Kentaro Kobayashi, Tomomi Tani, Takeharu Nagai
  "Conjugation of both on-axis and off-axis light in Nipkow disk confocal microscope to increase availability of incoherent light source."
  Cell Structure and Function, 36:237-246, 2011
• 堀川一樹，永井健治
  "細胞性粘菌の集合流形成における細胞間シグナル伝達"
  生物の科学 遺伝, 65:87-91, 2011
• Yoshiyuki Yamada, Takayuki Michikawa, Mitsuhiro Hashimoto, Kazuki Horikawa, Takeharu Nagai, Atsushi Miyawaki, Michael Häusser and Katsuhiko Mikoshiba
  "Quantitative comparison of genetically encoded Ca2+ indicators in cortical pyramidal cells and cerebellar Purkinje cells."
  Front Cell Neurosci, 5(18):40918, 2011
• Yongxin Zhao, Satoko Araki, Jiahui Wu, Takayuki Teramoto, Yu-Fen Chang, Masahiro Nakano, Ahmed S. Abdelfattah, Manabi Fujiwara, Takeshi Ishihara, Takeharu Nagai, Robert E. Campbell
  "An expanded palette of genetically encoded Ca2+ indicators."
  Science, 333:1888-1891, 2011
• 齋藤健太，永井健治
  "化学発光を利用した生理機能の可視化"
  化学と生物, 49:555-559, 2011
• Mami Nomura, Takeharu Nagai, Yoshie Harada and Tomomi Tani
  "Facilitated intracellular transport of TrkA by an interaction with nerve growth factor."
  Dev. Neurobiol., 71(1):634-649, 2011
• Yang L, Matsuda T, Raviraj V, Nagai T. and Soon L L.
  "Imaging the Dynamics of Intracellular Protein Translocation by Photoconversion of Phamret-Cybr/ROM."
  Journal of Microscopy, 242(3):250-261, 2011
• Kiwamu Takemoto, Tomoki Matsuda, Mark McDougall, Dieter H. Klaubert, Akira Hasegawa, Georgyi V. Los, Keith V. Wood, Atsushi Miyawaki and Takeharu Nagai
  "Chromophore-assisted light inactivation of HaloTag fusion proteins labeled with eosin in living cells"
  ACS Chem. Biol., 6(5):401–406, 2011
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平成26-27年度公募班

A01公募班　茅 元司

• 茅元司
  "1分子レーザートラップ顕微鏡によるアクチンとミオシンの物理化学的ダイナミクスの解析．特集「生化学に新たな視点を与える技術の開発と応用」"
  生化学, 86:174-183, 2014
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A01公募班　井上 圭一

• Keiichi Inoue, Takashi Tsukamoto and Yuki Sudo
  "Molecular and evolutionary aspects of microbial sensory rhodopsins"
  Biochim. Biophys. Acta, Bioenergetics, 1837(5):562-77, 2014
• Kengo Sasaki, Takahiro Yamashita, Kazuho Yoshida, Keiichi Inoue, Yoshinori Shichida, Hideki Kandori
  "Chimeric Proton-Pumping Rhodopsins Containing the Cytoplasmic Loop of Bovine Rhodopsin"
  PLOS ONE, 9(3):e91323, 2014
• Hayato Yamashita, Keiichi Inoue, Mikihiro Shibata, Takayuki Uchihashi, Jun Sasaki, Hideki Kandori and Toshio Ando
  "Role of trimer-trimer interaction of bacteriorhodopsin studied by optical spectroscopy and high-speed atomic force microscopy"
  Journal of Structural Biology, 184(1):2-11, 2013
• 井上圭一
  "新奇光駆動型Na+/H+ハイブリッドポンプロドプシンの発見とイオン輸送メカニズム"
  化学と工業, 66:642-643, 2013
• Takashi Tsukamoto, Keiichi Inoue, Hideki Kandori, and Yuki Sudo
  "Thermal and spectroscopic characterization of a proton pumping rhodopsin from an extreme thermophile"
  The Journal of Biological Chemistry, 288(30):21581-92, 2013
• Yuki Sudo, Ayako Okazaki, Hikaru Ono, Jin Yagasaki, Seiya Sugo, Motoshi Kamiya, Louisa Reissig, Keiichi Inoue, Kunio Ihara, Hideki Kandori, Shin Takagi and Shigehiko Hayashi
  "A blue-shifted light-driven proton pump for neural silencing"
  The Journal of Biological Chemistry, 288:20624-20632, 2013
• Keiichi Inoue, Hikaru Ono, Rei Abe-Yoshizumi, Susumu Yoshizawa, Hiroyasu Ito, Kazuhiro Kogure and Hideki Kandori
  "A light-driven sodium ion pump in marine bacteria"
  Nature Communications, 4:1678, 2013
• 井上圭一
  "拡がる微生物型ロドプシンの世界とその応用－バクテリオロドプシンの発見からオプトジェネティクスへ"
  化学と工業, 66:218-219, 2013
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A01公募班　藤原 敬宏

• Naoko Komura, Kenichi G.N. Suzuki, Hiromune Ando, Miku Konishi, Makiko Ikeda, Akihiro Imamura, Rahul Chadda, Takahiro K. Fujiwara, Hisae Tsuboi, Ren Sheng, Wonhwa Cho, Koichi Furukawa, Keiko Furukawa, Yoshio Yamauchi, Hideharu Ishida, Akihiro Kusumi, and Makoto Kiso
  "Raft-based interactions of gangliosides with a GPI-anchored receptor"
  Nat. Chem. Biol., in press
• Takahiro K. Fujiwara, Kokoro Iwasawa, Ziya Kalay, Taka A. Tsunoyama, Yusuke Watanabe, Yasuhiro M. Umemura, Hideji Murakoshi, Kenichi G.N. Suzuki, Yuri L. Nemoto, Nobuhiro Morone, and Akihiro Kusumi
  "Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane"
  Mol. Biol. Cell, 27:1101-1119, 2016
• Shingo Sotoma, Jun Iimura, Ryuji Igarashi, Koichiro M. Hirosawa, Hidenori Ohnishi, Shin Mizukami, Kazuya Kikuchi, Takahiro K. Fujiwara, Masahiro Shirakawa, and Hidehito Tochio
  "Selective labeling of proteins on living cell membranes using fluorescent nanodiamond probes"
  Nanomaterials, 6:56, 2016
• Seong-Wook Oh, Koji Onomoto, Mai Wakimoto, Kazuhide Onoguchi, Fumiyoshi Ishidate, Takahiro Fujiwara, Mitsutoshi Yoneyama, Hiroki Kato, and Takashi Fujita
  "Leader-containing uncapped viral transcript activates RIG-I in antiviral stress granules"
  PLoS Pathog., 12:e1005444, 2016
• Akihiro Kusumi, Taka A. Tsunoyama, Koichiro M. Hirosawa, Rinshi S. Kasai, and Takahiro K. Fujiwara
  "Tracking single molecules at work in living cells"
  Nat. Chem. Biol., 10:524-532, 2014
• Nao Hiramoto-Yamaki, Kenji A.K. Tanaka, Kenichi G.N. Suzuki, Koichiro M. Hirosawa, Manami S.H. Miyahara, Ziya Kalay, Koichiro Tanaka, Rinshi S. Kasai, Akihiro Kusumi, and Takahiro K. Fujiwara
  "Ultrafast diffusion of a fluorescent cholesterol analog in compartmentalized plasma membranes"
  Traffic, 15:583-612, 2014
• Ziya Kalay, Takahiro K. Fujiwara, Akihisa Otaka, and Akihiro Kusumi
  "Lateral diffusion in a discrete fluid membrane with immobile particles"
  Phys. Rev. E, 89:22724, 2014
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A01公募班　原田 慶恵

• Yong-Woon Han, Hiroshi Sugiyama and Yoshie Harada
  "The application of Fluorescence-Conjugated Pyrrole/Imidazole Polyamides in the Characterization of Protein-DNA Complex Formation"
  Biomater. Sci., 2016, 4:391399, 2016
• Shingo Sotoma, Ryuji Igarashi, Jun Iimura, Yuta Kumiya, Hidehito Tochio, Yoshie Harada and Masahiro Shirakawa
  "Suppression of Nonspecific Protein-Nanodiamond Adsorption Enabling Specific Targeting of Nanodiamonds to Biomolecules of Interest"
  Chemistry Letters, 44(3):354-356, 2015
• Takuma Iwasa, Yong-Woon Han, Ryo Hiramatsu, Hiroaki Yokota, Kimiko Nakao, Ryuji Yokokawa, Teruo Ono and Yoshie Harada
  "Synergistic effect of ATP for RuvA–RuvB–Holliday junction DNA complex formation"
  Scientific Reports, 5:18177, 2015
• Ikumi Oomoto, Asuka Suzuki-Hirano, Hiroki Umeshima, Yong-Woon Han, Hiroyuki Yanagisawa, Peter Carlton, Yoshie Harada, Mineko Kengaku, Akimitsu Okamoto, Tomomi Shimogori and Dan Ohtan Wang
  "ECHO-liveFISH: in vivo RNA labeling reveals dynamic regulation of nuclear RNA foci in living tissues"
  Nucl. Acids Res., 43(19):e126, 2015
• Yosuke Yoshinari, Shigeyuki Mori, Ryuji Igarashi, Takuma Sugi, Hiroaki Yokota, Kazuhiro Ikeda, Hitoshi Sumiya, Ikue Mori, Hidehito Tochio, Yoshie Harada and Masahiro Shirakawa
  "Optically Detected Magnetic Resonance of Nanodiamonds In Vivo; Implementation of Selective Imaging and Fast Sampling."
  Journal of Nanoscience and Nanotechnology, 15:1014-1021, 2015
• Shingo Sotoma, Kenichi Akagi, Saburo Hosokawa, Ryuji Igarashi, Hidehito Tochio, Yoshie Harada and Masahiro Shirakawa
  "Comprehensive and quantitative analysis for controlling the physical/chemical states and particle properties of nanodiamonds for biological applications"
  RSC Advances, 5:13818-13827, 2015
• Shingo Sotoma, Yohsuke Yoshinari, Ryuji Igarashi, Akiyoshi Yamazaki, Shige H. Yoshimura, Hidehito Tochio, Masahiro Shirakawa and Yoshie Harada
  "Effective production of fluorescent nanodiamonds containing negatively-charged nitrogen-vacancy centers by ion irradiation"
  Diamond and Related Materials, 49:33-38, 2014
• Wakako Sadaie, Yoshie Harada, Michiyuki Matsuda and Kazuhiro Aoki
  "Quantitative In Vivo Fluorescence Cross-Correlation Analyses Highlight the Importance of Competitive Effects in the Regulation of Protein-Protein Interactions"
  Molecular and Cellular Biology, 34 no.17:3272-3290, 2014
• Yoshitaka Shirasaki, Mai Yamagishi, Nobutake Suzuki, Kazushi Izawa, Asahi Nakahara, Jun Mizuno, Shuichi Shoji, Toshio Heike, Yoshie Harada, Ryuta Nishikomori, Osamu Ohara
  "Real-time single-cell imaging of protein secretion."
  Scientific Reports, 4:4736, 2014
• Yasuko Osakada, Guillem Pratx, Conroy Sun, Masanori Sakamoto, Moiz Ahmad, Olga Volotskova, Qunxiang Ong, Toshiharu Teranishi, Yoshie Harada, Lei Xing and Bianxiao Cui
  "Hard X-ray-induced optical luminescence via　biomolecule-directed metal clusters."
  Chemical Communications, 27:3549-3551, 2014
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A01公募班　村越 秀治

• Takahiro Fujiwara, Kokoro Iwasawa, Ziya Kalay, Takaaki Tsunoyama, Yusuke Watanabe, Yasuhiro Umemura, Hideji Murakoshi, Kenichi Suzuki, Yuri Nemoto, Nobuhiro Morone and Akihiro Kusumi
  "Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane."
  Mol Biol Cell, in press
• Hideji Murakoshi and Ryohei Yasuda
  "Imaging signal transduction in dendrites using genetically-encoded fluorescent proteins."
  Springer-Verlag, in press
• Hideji Murakoshi, Akihiro Shibata, Yoshihisa Nakahata and Junichi Nabekura
  "A dark green fluorescent protein as an acceptor for measurement of Förster resonance energy transfer by fluorescence lifetime imaging microscopy."
  Scientific Reports, 5:15334, 2015
• Hideji Murakoshi and Akihiro Shibata
  "Optogenetic imaging of protein activity in the synapse by using 2-photon fluorescence lifetime imaging microscopy."
  Springer-Verlag, --:185-197, 2015
• Akihiro Shibata, Hiroshi Maebashi, Yoshihisa Nakahata, Junichi Nabekura and Hideji Murakoshi
  "Development of a molecularly evolved, highly sensitive CaMKII FRET sensor with improved expression pattern."
  PLoS ONE, 10:e0121109, 2015
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A01公募班　城口 克之

• 城口克之
  "Digital RNA Sequencing"
  JSI Newsletter, 24(2):21, 2016
• *Huiyi Chen, *Katsuyuki Shiroguchi, Hao Ge, X. Sunney Xie (* equal contributions)
  "Genome-wide study of mRNA degradation and transcript elongation in Escherichia coli"
  Molecular Systems Biology, 11:781, 2015
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平成24-25年度公募班

A01公募班　井上 圭一

• Kengo Sasaki, Takahiro Yamashita, Kazuho Yoshida, Keiichi Inoue, Yoshinori Shichida, Hideki Kandori
  "Chimeric Proton-Pumping Rhodopsins Containing the Cytoplasmic Loop of Bovine Rhodopsin"
  PLOS ONE, in press, 2014
• Yuki Sudo, Ayako Okazaki, Hikaru Ono, Jin Yagasaki, Seiya Sugo, Motoshi Kamiya, Louisa Reissig, Keiichi Inoue, Kunio Ihara, Hideki Kandori, Shin Takagi and Shigehiko Hayashi
  "A blue-shifted light-driven proton pump for neural silencing"
  The Journal of Biological Chemistry, in press
• Takashi Tsukamoto, Keiichi Inoue, Hideki Kandori, and Yuki Sudo
  "Thermal and spectroscopic characterization of a proton pumping rhodopsin from an extreme thermophile"
  The Journal of Biological Chemistry, in press
• Keiichi Inoue, Takashi Tsukamoto and Yuki Sudo
  "Molecular and evolutionary aspects of microbial sensory rhodopsins"
  Biochim. Biophys. Acta, Bioenergetics, in press
• Keiichi Inoue, Hikaru Ono, Rei Abe-Yoshizumi, Susumu Yoshizawa, Hiroyasu Ito, Kazuhiro Kogure and Hideki Kandori
  "A light-driven sodium ion pump in marine bacteria"
  Nature Communications, in press
• Hayato Yamashita, Keiichi Inoue, Mikihiro Shibata, Takayuki Uchihashi, Jun Sasaki, Hideki Kandori and Toshio Ando
  "Role of trimer-trimer interaction of bacteriorhodopsin studied by optical spectroscopy and high-speed atomic force microscopy"
  Journal of Structural Biology, in press
• 井上圭一
  "新奇光駆動型Na+/H+ハイブリッドポンプロドプシンの発見とイオン輸送メカニズム"
  化学と工業, 66:642-643, 2013
• 井上圭一
  "拡がる微生物型ロドプシンの世界とその応用－バクテリオロドプシンの発見からオプトジェネティクスへ"
  化学と工業, 66:218-219, 2013
Page Top

A01公募班　山下 高廣

• Kengo Sasaki, Takahiro Yamashita, Kazuho Yoshida, Keiichi Inoue, Yoshinori Shichida and Hideki Kandori
  "Chimeric Proton-Pumping Rhodopsins Containing the Cytoplasmic Loop of Bovine Rhodopsin"
  PLOS ONE, 9:e91323, 2014
• Ryo Maeda, Michio Hiroshima, Takahiro Yamashita, Akimori Wada, Shoko Nishimura, Yasushi Sako, Yoshinori Shichida and Yasushi Imamoto
  "Single-Molecule Observation of the Ligand-Induced Population Shift of Rhodopsin, A G-Protein-Coupled Receptor."
  Biophysical Journal, 106:915-924, 2014
• Keiichi Kojima, Yasushi Imamoto, Ryo Maeda, Takahiro Yamashita and Yoshinori Shichida
  "Rod Visual Pigment Optimizes Active State to Achieve Efficient G protein Activation as Compared to Cone Visual Pigments."
  Journal of Biological Chemistry, 289(8):5061-73, 2014
• Takahiro Yamashita, Katsuhiko Ono, Hideyo Ohuchi, Akane Yumoto, Hitoshi Gotoh, Sayuri Tomonari, Kazumi Sakai, Hirofumi Fujita, Yasushi Imamoto, Sumihare Noji, Katsuki Nakamura and Yoshinori Shichida
  "Evolution of mammalian Opn5 as a specialized UV-absorbing pigment by a single amino acid mutation."
  Journal of Biological Chemistry, 289(7):3991-4000, 2014
• Masataka Yanagawa, Takahiro Yamashita and Yoshinori Shichida
  "Glutamate acts as a partial inverse agonist to metabotropic glutamate receptor with a single amino acid mutation in the transmembrane domain"
  Journal of Biological Chemistry, 288:9593-9601, 2013
• Yasushi Imamoto, Ichirota Seki, Takahiro Yamashita and Yoshinori Shichida
  "Efficiencies of activation of transducin by cone and rod visual pigments"
  Biochemistry, 52:3010-3018, 2013
• Takahiro Yamashita, Shuhei Nakamura, Kei Tsutsui, Takefumi Morizumi and Yoshinori Shichida
  "Chloride-Dependent Spectral Tuning Mechanism of L-Group Cone Visual Pigments"
  Biochemistry, 52:1192-1197, 2013
• Take Matsuyama, Takahiro Yamashita, Yasushi Imamoto, and Yoshinori Shichida
  "Photochemical Properties of Mammalian Melanopsin."
  Biochemistry, 51:5454-5462, 2012
• Keita Sato, Takahiro Yamashita, Yasushi Imamoto, and Yoshinori Shichida
  "Comparative studies on the late bleaching processes of four kinds of cone visual pigments and rod visual pigment."
  Biochemistry, 51:4300-4308, 2012
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A01公募班　藤原 敬宏

• 楠見明弘、鈴木健一、藤原敬宏、笠井倫志
  "１分子イメージングによる細胞膜シグナル変換機構の解明"
  生体の科学, 64:539-544, 2013
• Itaru Imayoshi, Akihiro Isomura, Yukiko Harima, Kyogo Kawaguchi, Hiroshi Kori, Hitoshi Miyachi, Takahiro Fujiwara, Fumiyoshi Ishidate and Ryoichiro Kageyama
  "Oscillatory control of factors determining multipotency and fate in mouse neural progenitors"
  Science, 342:1203-1208, 2013
• Ikuko Koyama-Honda, Eisuke Itakura, Takahiro K. Fujiwara and Noboru Mizushima
  "Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome formation site"
  Autophagy, 9:1491-1499, 2013
• N. Yoshikawa, H. Hirori, H. Watanabe, T. Aoki, T. Ihara, R. Kusuda, C. Wolpert, T.K. Fujiwara, A. Kusumi, Y. Kanemitsu and K. Tanaka
  "Biexciton state causes photoluminescence fluctuations in CdSe/ZnS core/shell quantum dots at high photoexcitation densities"
  Phys. Rev. B, 88:155440, 2013
• Hirohito Nishimura, Ken Ritchie, Rinshi S. Kasai, Miki Goto, Nobuhiro Morone, Hiroyuki Sugimura, Koichiro Tanaka, Ichiro Sase, Akihiko Yoshimura, Yoshitaro Nakano, Takahiro K. Fujiwara and Akihiro Kusumi
  "Biocompatible fluorescent silicon nanocrystals for single-molecule tracking and fluorescence imaging"
  J. Cell Biol., 202:967-983, 2013
• 藤原敬宏、笠井倫志、楠見明弘
  "超高速･超解像１蛍光分子顕微鏡"
  現代化学, 508:50-51, 2013
• Akihiro C.E. Shibata, Limin H. Chen, Rie Nagai, Fumiyoshi Ishidate, Rahul Chadda, Yoshihiro Miwa, Keiji Naruse, Yuki M. Shirai, Takahiro K. Fujiwara, and Akihiro Kusumi
  "Rac1 recruitment to the archipelago structure of the focal adhesion through the fluid membrane as revealed by single-molecule analysis"
  Cytoskeleton, 70:161-177, 2013
• Ren Sheng, Yong Chen, Heon Yung Gee, Ewa Stec, Heather R. Melowic, Nichole R. Blatner, Moe P. Tun, Yonjung Kim, Morten Källberg, Takahiro K. Fujiwara, Ji Hye Hong, Kwang Pyo Kim, Hui Lu, Akihiro Kusumi, Min Goo Lee, and Wonhwa Cho
  ""Cholesterol modulates cell signaling and protein networking by specifically interacting with PDZ domain-containing scaffold proteins""
  Nature Communications, 3:1249, 2012
• Akihiro Kusumi, Takahiro K. Fujiwara, Rahul Chadda, Min Xie, Takaaki A. Tsunoyama, Ziya Kalay, Rinshi S. Kasai, and Kenichi G.N. Suzuki
  "Dynamic organizing principles of the plasma membrane that regulate signal transduction: Commemorating the 40th anniversary of the Singer-Nicolson's fluid mosaic model"
  Annual Review of Cell and Developmental Biology, 28:215-250, 2012
• Akihiro Kusumi, Takahiro K. Fujiwara, Rahul Chadda, Min Xie, Takaaki A. Tsunoyama, Ziya Kalay, Rinshi S. Kasai and Kenichi G.N. Suzuki
  "Dynamic organizing principles of the plasma membrane that regulate signal transduction"
  Annu. Rev. Cell Dev. Biol., 28:215-250, 2012
• Kenich G.N. Suzuki, Rinshi S. Kasai, Koichiro M. Hirosawa, Yuri L. Nemoto, Munenori Ishibashi, Yoshihiro Miwa, Takahiro K. Fujiwara, and Akihiro Kusumi
  "Transient GPI-anchored protein homodimers are units for raft organization and function"
  Nature Chemical Biology, 8:774-783, 2012
• Akihiro C.E. Shibata, Takahiro K. Fujiwara, Limin Chen, Kenichi G.N. Suzuki, Yoshiro Ishikawa, Yuri L. Nemoto, Yoshihiro Miwa, Rahul Chadda, Keiji Naruse, and Akihiro Kusumi
  "Archipelago architecture of the focal adhesion: Membrane molecules freely enter and exit from the focal adhesion zone"
  Cytoskeleton, 69:380-392, 2012
• Akihiro Kusumi, Takahiro K. Fujiwara, Nobuhiro Morone, Kenta J. Yoshida, Rahul Chadda, Min Xie, Rinshi S. Kasai, and Kenichi G.N. Suzuki
  "Membrane mechanisms for signal transduction: The coupling of the meso-scale raft domains to membrane-skeleton-induced compartments and dynamic protein complexes"
  Seminars in Cell and Developmental Biology, 23:126-144, 2012
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A01公募班　水上 進

• Satoshi Okada, Shin Mizukami, Takao Sakata, Yutaka Matsumura, Yoshichika Yoshioka and Kazuya Kikuchi
  "Ratiometric MRI Sensors Based on Core-Shell Nanoparticles for Quantitative pH Imaging"
  Adv. Mater., 26(19):2989–2992, 2014
• Akimasa Yoshimura, Shin Mizukami, Yuki Mori, Yoshichika Yoshioka and Kazuya Kikuchi
  "1H MRI Detection of Gene Expression in Living Cells by Using Protein Tag and Biotinylation Probe"
  Chem. Lett., 43(2):219-221, 2014
• Hisashi Matsushita, Shin Mizukami, Fuminori Sugihara, Yosuke Nakanishi, Yoshichika Yoshioka and Kazuya Kikuchi
  "Multifunctional Core-shell Silica Nanoparticles for Highly Sensitive 19F Magnetic Resonance Imaging"
  Angew. Chem. Int. Ed., 53(4):1008-11, 2014
• Shin Mizukami, Yuichiro Hori and Kazuya Kikuchi
  "Small-Molecule Based Protein-Labeling Technology in Live Cell Studies: Probe-Design Concepts and Applications"
  Acc. Chem. Res., 47 (1):247–256, 2014
• Satoshi Okada, Shin Mizukami, Yutaka Matsumura, Yoshichika Yoshioka and Kazuya Kikuchi
  "Nanospherical Polymer as an MRI Sensor without Paramagnetic or Superparamagnetic Species"
  Dalton Trans., 42:15864-15867, 2013
• Daisuke Yamazaki, Yosuke Funato, Jiro Miura, Sunao Sato, Satoru Toyosawa, Kazuharu Furutani, Yoshihisa Kurachi, Yoshihiro Omori, Takahisa Furukawa, Tetsuya Tsuda, Susumu Kuwabata, Shin Mizukami, Kazuya Kikuchi and Hiroaki Miki
  "Basolateral Mg2+ Extrusion via CNNM4 Mediates Transcellular Mg2+ Transport across Epithelia: A Mouse Model"
  PLOS Genet., 9:e1003983, 2013
• Tatsuya Nakamura, Shin Mizukami, Miho Tanaka and Kazuya Kikuchi
  "Efficient Development of Luminescent Lanthanide(III) Complexes by Solid-Phase Synthesis and On-Resin Screening"
  Chem. Asian J., 8:2685-2690, 2013
• Eric Lindberg, Shin Mizukami, Keiji Ibata, Atsushi Miyawaki and Kazuya Kikuchi
  "Development of Luminescent Coelenterazine Derivatives Activatable by β-Galactosidase for Monitoring Dual Gene Expression"
  Chem. Eur. J., 19:14970-14976, 2013
• Eric Lindberg, Shin Mizukami, Keiji Ibata, Takashi Fukano, Atsushi Miyawaki and Kazuya Kikuchi
  "Development of Cell-Impermeable Coelenterazine Derivatives"
  Chem. Sci., 4:4395-4400, 2013
• 水上進
  "ナノ粒子設計に基づく機能性1H MRIプローブの開発"
  薬学雑誌, 133:351-354, 2013
• 水上進・菊地和也
  "細胞蛋白質への機能性分子ラベリング技術"
  未来材料, 2:2-5, 2013
• Junichi Kikuta, Yoh Wada, Toshiyuki Kowada, Ge-Hong Sun-Wada, Issei Nishiyama, Shin Mizukami, Nobuhiko Maiya, Hisataka, Yasuda, Atsushi Kumanogoh, Kazuya Kikuchi, Ronald Germain, Masaru Ishii
  "Dynamic Visualization of RANKL and Th17-mediated Control of Osteoclast Function"
  J. Clin. Invest., 123:866–873, 2013
• Kalyan K. Sadhu, Shin Mizukami and Kazuya Kikuchi
  "pH Induced Dual "OFF-ON-OFF" Switch: Influence of Suitably Placed Carboxylic Acid"
  Org. Biomol. Chem, 11:563-568, 2013
• Zhanghua Zeng, Shin Mizukami and Kazuya Kikuchi
  "Simple and Real-time Colorimetric Assay for Glycosidases Activity Using Functionalized Gold Nanoparticles and its Application for Inhibitor Screening"
  Anal. Chem., 84:9089-9095, 2012
• Reisuke Baba, Yuichiro Hori, Shin Mizukami, Kazuya Kikuchi
  "Development of a Fluorogenic Probe with a Transesterification Switch for Detection of Histone Deacetylase Activity"
  J. Am. Chem. Soc., 134:14310–14313, 2012
• Hisashi Matsushita, Shin Mizukami, Yuki Mori, Fuminori Sugihara, Masahiro Shirakawa, Yoshichika Yoshioka and Kazuya Kikuchi
  "19F MRI monitoring of Gene Expression in Living Cells via Cell Surface β-Lactamase Activity"
  ChemBioChem, 13:1579-1583, 2012
• Yuichiro Hori, Kyohei Nakaki, Motoki Sato, Shin Mizukami and Kazuya Kikuchi
  "Development of Protein Labeling Probes with Redesigned Fluorogenic Switch Based on Intramolecular Association and No-wash Live-cell Imaging"
  Angew. Chem. Int. Ed., 51:5611-5614, 2012
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A01公募班　高橋 章

• Akihiro Shirai, Mutsumi Aihara, Akira Takahashi, Hideaki Maseda and Takeshi Omasa
  "Synergistic antimicrobial activity based on the combined use of a gemini-quaternary ammonium compound and ultraviolet A light"
  Journal of Photochemistry and Photobiology, 130C:226-233, 2013
• Kadomura-Ishikawa Yasuko, Miyawaki Katsuyuki, Noji Sumihare and Takahashi Akira
  "Phototropin 2 is involved in blue light-induced anthocyanin accumulation in Fragaria x ananassa fruits."
  Journal of Plant Research, 126:847-857, 2013
• Atsushi Hashimoto, Kazuaki Mawatari, Yohsuke Kinouchi, Masatake Akutagawa, Naotomo Ota, Kazuyuki Nishimura, Tsuyoshi Hirata and Akira Takahashi
  "Inactivation of MS2 Phage and Cryptosporidium parvum Oocysts Using UV-A from High-Intensity Light-Emitting Diode for Water Disinfection"
  Journal of Water and Environment Technology, 11:299-307, 2013
• Takafumi Yakabe, Takaaki Shimohata and Akira Takahashi
  "Lactobacillus brevis KB290 enhances IL-8 secretion by Vibrio parahaemolyticus-infected Caco-2 cells"
  Journal of Microbiology and Biotechnology, 23:118-124, 2013
• Tam Thi Thanh Le, Kazuaki Mawatari, Miki Maetani, Tomomi Yamamoto, Sayaka Hayashida, Hitomi Iba, Mutsumi Aihara, Akiko Hirata, Takaaki Shimohata, Takashi Uebanso and Akira Takahashi
  "VP2118 has major roles in Vibrio parahaemolyticus response to oxidative stress"
  Biochimica et Biophysica Acta, 1820:1686-1692, 2012
• Takaaki Shimohata, Kazuaki Mawatari, Hitomi Iba, Masakazu Hamano, Sachie Negoro, Shoko Asada, Mutsumi Aihara, Akiko Hirata, Zehong Su and Akira Takahashi
  "VopB1 and VopD1 are essential for type III secretion system 1 effector translocation in Vibrio parahaemolyticus"
  Canadian Journal of Microbiology, 58:1002-1007, 2012
• Masayuki Nakano, Eiki Yamasaki, Akitoyo Ichinose, Takaaki Shimohata, Akira Takahashi, Junko K Akada, Kazuyuki Nakamura, Joel Moss, Toshiya Hirayama and Hisao Kurazono
  "Salmonella enterotoxin (Stn) regulates membrane composition and integrity"
  Dis Model Mech, 5:515-521, 2012
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A01公募班　村越 秀治

• Akiyoshi Uezu, Hirokazu Okada, Hideji Murakoshi, Cosmo D. del Vescovo, Ryohei Yasuda, Dario Diviani and Scott H. Soderling
  "A Modified SH2 Domain to Phototrap and Identify Phosphotyrosine Proteins from Subcellular Sites within Cells."
  Proc Natl Acad Sci U S A, 109:E2929- E2938, 2012
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